Comparison of an Avidin-Biotin Immunoassay With Three Commercially Available Immunofluorescence Kits for Typing of Herpes Simplex Virus

Document Type

Article

Journal/Book Title/Conference

Comparison of an avidin-biotinimmunoassay with three commercially available immunofluorescence kits for typing of herpessimplex virus

Volume

38

Publication Date

1985

First Page

1158

Last Page

1162

Abstract

An avidin-biotin complex system was compared with three commercially available immunofluorescence kits for serotyping herpes simplex virus isolates from clinical specimens. Sensitivity values showed that the Electro-Nucleonics and Immulok reagents were useful in detecting the presence of virus, whereas the predictive values showed that the Syva and Immulok reagents possessed adequate discrimination between the herpes simplex virus serotypes. The avidin-biotin complex system was equal or superior to the immunofluorescence reagents tested both in detecting herpes simplex virus antigens in cell culture and in serotyping herpes simplex virus isolates.

Comments

J. Clin. Pathol. 38: 1158-1162. PMID: 2997305

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