Transgenic Animal Production an Animal Biotechnology
Document Type
Article
Journal/Book Title/Conference
Theriogenology
Volume
67
Publication Date
1-1-2007
First Page
127
Last Page
133
Abstract
Considerable progress has been made in methods for production of transgenic livestock; beginning with pronuclear microinjection over 20 years ago. New methods, including the use of viral vectors, sperm-mediated gene transfer and somatic cell cloning, have overcome many of the limitations of pronuclear microinjection. It is now possible to not only readily make simple insertional genetic modifications, but also to accomplish, more complex, homozygous gene targeting and artificial chromosome transfer in livestock.
Recommended Citation
Robl JM., Wang Z., Kasinathan P., Kuroiwa Y. Transgenic animal production and animal biotechnology. Theriogenology (2007) 67(1):127-33.
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