Nephrotoxicity of Easter Lily (Lilium longiflorum)

Document Type

Contribution to Book

Journal/Book Title/Conference

Poisonous Plants: Global Research and Solutions

Editor

K Panter, T Wierenga and J Pfister

Publisher

CAB International Press

Publication Date

2007

First Page

271

Last Page

278

Abstract

This study was conducted to determine the toxicity of Easter lily to a cat, rats and rabbits administered or fed Easter lily leaves. It was shown that the cat vomited >95% of the administered Easter lily leaves. The cat also showed profuse salivation, polyuria, altered serum biochemical and haematological values and kidney lesions. No clinicopathological or histopathological changes were observed in the rats and rabbits. The clinicopathological, histopathological, treatment and outcome of Easter lily poisoning in cats as recorded by the National Animal Poison Control Centre (NAPCC) in the USA are also described. The results indicate that Easter lily is uniquely nephrotoxic to cats. Broader themes include plant biochemistry, toxic effects in animals and humans, and rangeland management approaches to prevent poisoning amongst others. Individual chapters address plant animal relationships, various classes of secondary plant compounds, isolation, identification and effects of these toxins on biological mammalian systems and analytical methods, diagnostic tools and management strategies for plant toxicoses in animals and humans.

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