A Mule Cloned from Fetal Cells by Nuclear Transfer

Authors

G. L. Woods
Kenneth L. White, Utah State UniversityFollow
D. K. Vanderwall
G. Li
K. I. Ashton
Tom D. Bunch, Utah State UniversityFollow
L. N. Meerdo
B. Pate

Document Type

Article

Journal/Book Title/Conference

Science

Volume

301

Issue

5636

Publication Date

2003

First Page

1063

Last Page

1063

Abstract

Nuclear transfer was used to produce a cloned mule, a sterile hybrid equine species. Mules result from breeding a male donkey (Equus asinus, 62 chromosomes) with a female horse (Equus caballus, 64 chromosomes), producing an animal with 63 chromosomes. Equine cloning has been hampered by a lack of optimal in vitro oocyte maturation and embryo culture systems (1), and previous reports of nuclear transfer pregnancies have been less than 65 days of development in utero (2).

Recommended Citation

Woods, G.L., K.L. White, D.K. Vanderwall, G. Li, K.I. Aston, T.D. Bunch, L.N. Meerdo and B. Pate 2003. A Mule Cloned from Fetal Cells by Nuclear Transfer Science 301(5636): 1063.