"Functional dissection and module swapping of fungal cyclooligomer deps" by Dayu Yu, fuchao xu et al.
 

Document Type

Article

Journal/Book Title

ChemComm

Publication Date

5-2013

Abstract

BbBSLS and BbBEAS were dissected and reconstituted in Saccharomyces cerevisiae. The intermodular linker is essential for the reconstitution of the separate modules. Module 1 can be swapped between BbBEAS and BbBSLS, while modules 2 and 3 control the product profiles. BbBSLS is a flexible enzyme that also synthesizes beauvericins.

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