Predictable Enzymatic Glycosylation

Document Type

Article

Journal/Book Title

Chemistry & Biology

Publication Date

6-26-2009

Publisher

Elsevier

Volume

16

Issue

6

First Page

579

Last Page

580

Abstract

An innovative approach for manipulating glycosyltransferase-catalyzed glycosylation has now been developed (Truman et al.). Created using a domain-swapping strategy, these chimeric glycotransferases have predictable substrate specificity and may lead to the breakthrough developments in the preparation of carbohydrate-containing molecules of biological interest.

Comments

PubMed PMID: 19549595

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