Date of Award:

5-1-1965

Document Type:

Thesis

Degree Name:

Master of Science (MS)

Department:

Biology

Department name when degree awarded

Physiology

Committee Chair(s)

T. L. Bahler

Committee

T. L. Bahler

Abstract

It has been known for some time that eosinophilia, either local or peripheral, is associated in some manner with the antigen-antibody reaction. Several theories have been proposed to explain this phenomenon. The most prominent of these theories at the present time is that proposed by Code (1944) and strongly supported by Archer (1963). These investigators contend that the release of histamine at the site of the antigen antibody reaction attracts eosinophils to the area. Litt (1964a), on the other hand, reject the eosinophilatactic function of histamine, but believes that the function of the eosinophil is to phagocytize the antigen antibody complex. Another theory, proposed and supported by Spiers and his co-workers (Spiers, 1958; Spiers, Osada and Jansen, 1960), indicates that eosinophils function in antibody formation.

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