Neuropsychiatric Symptoms in Dementia Patients With and Without a History of Traumatic Brain Injury

Authors

Vani Rao, John Hopkins School of Medicine in BaltimoreFollow
Paul Rosenberg, John Hopkins School of Medicine in Baltimore
Quincy Samus Miles, John Hopkins School of Medicine in Baltimore
Deepa Patadia, Northeaster Ohio Universities College of Medicine
Kate Treiber, Utah State University
Melaine Bertrand, John Hopkins School of Medicine in Baltimore
Maria C. Norton, Utah State UniversityFollow
Martin Steinberg, John Hopkins School of Medicine in Baltimore
Constantine Lyketsos, John Hopkins School of Medicine in Baltimore
JoAnn T. Tschanz, Utah State UniversityFollow

Document Type

Article

Journal/Book Title/Conference

Journal of Neuropsychiatry and Clinical Neurosciences

Volume

22

Issue

2

Publisher

American Neuropsychiatric Association

Publication Date

2010

First Page

166

Last Page

172

Abstract

The authors aim to determine if a history of traumatic brain injury (TBI) assessed before dementia onset is associated with a higher risk of neuropsychiatric symptoms after dementia onset. A population-based incident series of people with dementia were assessed for TBI prior to onset of dementia and for neuropsychiatric symptoms after the onset, using the Neuropsychiatric Inventory. Participants with predementia TBI were more likely to exhibit disinhibition (12.7% versus 5.4%, OR=2.8, p=0.02), but not other neuropsychiatric symptoms. Traumatic brain injury may increase the risk of disinhibition in patients with dementia.

Recommended Citation

Rao V, Rosenberg P, Miles QS, Patadia D, Treiber K, Bertrand M, Norton M, Steinberg M, Tschanz J, Lyketsos C. Neuropsychiatric symptoms in dementia patients with and without a history of traumatic brain injury. J Neuropsychiatry and Clin Neurosci, 22:166-172, 2010 Fulltext requires current subscription.