Effects of Combining Propofol and Alfentanil on Ventilation, Analgesia, Sedation and Emesis in Human Volunteers

Authors

D. J. Paylin
B. Coda
D. D. Shen
JoAnn T. Tschanz, Utah State UniversityFollow
Q. Nguyen
R. Schaffer
G. Donaldson
R. C. Jacobsen
C. R. Chapman

Document Type

Article

Journal/Book Title/Conference

Anesthesiology

Volume

84

Issue

1

Publisher

Lippincott, Williams & Wilkins

Publication Date

1996

First Page

23

Last Page

37

Abstract

Propofol and alfentanil frequently are administered together for intravenous sedation. This study investigated pharmacokinetic and pharmacodynamic interactions between propofol and alfentanil, at sedative concentrations, with specific regard to effects on ventilation, analgesia, sedation, and nausea.

Comments

Originally published by Lippincott, Williams & Wilkins. HTML fulltext available through remote link.

Recommended Citation

Pavlin DJ, Coda B, Shen DD, Tschanz J, Nguyen Q, Schaffer R, Donaldson G, Jacobson RC, Chapman CR. Effects of combining propofol and alfentanil on ventilation, analgesia, sedation and emesis in human volunteers. Anesthesiology 1996;84: 23-37.