Class
Article
College
College of Engineering
Department
English Department
Faculty Mentor
Jon Takemoto
Presentation Type
Poster Presentation
Abstract
Meso-biliverdin IXα (MBV) is a valuable bioproduct with antioxidant and cytoprotective properties that is of great interest and importance forthe medical industry as an anti-inflammatory, agricultural industry as a livestock feed additive, and other commercial applications. MBV is aheme-derivedbilinthat can be synthesized by chemical conversion of cyanobacterial phycocyanobilin (PCB). Phycocyanin (PC) is an abundantpigment composed of protein complexed with PCB and responsible for harvesting light for photosynthesis by cyanobacteria. Logan LagoonsCyanobacteria 2 (LLC2) is a novel strain of cyanobacteria recently discovered in Logan, Utah that produces PC in appreciable amounts. LLC2 iscapable of growing with shale/oil extraction-derived produced water as a substrate, making it a lucrative target for the production of MBV in thescope of a waste-to-value bioprocess. A prototype bioprocess is already commercially available for MBV production from another strain of cyanobacteria, Limnospirafusiformis. Here, we aim to develop a parallel but environmentally sustainable and commercially viable bioprocessfor MBV production using oil/shale waste produced water and LLC2. The bioprocess will adhere to an array of standards and constraints. Lead levels within LLC2 growths cannot exceed a maximum value of 15 µg per amount of MBV consumed daily, and there must be no detectable BMAA levels. Additional economic and manufacturing constraints include wastewater processing to eliminate any potential toxins as well asscale-up to commercial-level production on rotating algal biofilm reactors (RABRs). This project highlights the bioprocess development processfrom initial culture, algal biomass growth on laboratory scale RABRs, scale-up to a greenhouse scale RABR, PCB extraction, and conversion toMBV. This project concludes that MBV production is possible from LLC2 dervied PCB, with both lead and BMAA levels within the given tolerances.
Location
Logan, UT
Start Date
4-8-2022 12:00 AM
Included in
Meso-Biliverdin IXα Production by Conversion of Cyanobacteria-Derived Phycocyanobilin
Logan, UT
Meso-biliverdin IXα (MBV) is a valuable bioproduct with antioxidant and cytoprotective properties that is of great interest and importance forthe medical industry as an anti-inflammatory, agricultural industry as a livestock feed additive, and other commercial applications. MBV is aheme-derivedbilinthat can be synthesized by chemical conversion of cyanobacterial phycocyanobilin (PCB). Phycocyanin (PC) is an abundantpigment composed of protein complexed with PCB and responsible for harvesting light for photosynthesis by cyanobacteria. Logan LagoonsCyanobacteria 2 (LLC2) is a novel strain of cyanobacteria recently discovered in Logan, Utah that produces PC in appreciable amounts. LLC2 iscapable of growing with shale/oil extraction-derived produced water as a substrate, making it a lucrative target for the production of MBV in thescope of a waste-to-value bioprocess. A prototype bioprocess is already commercially available for MBV production from another strain of cyanobacteria, Limnospirafusiformis. Here, we aim to develop a parallel but environmentally sustainable and commercially viable bioprocessfor MBV production using oil/shale waste produced water and LLC2. The bioprocess will adhere to an array of standards and constraints. Lead levels within LLC2 growths cannot exceed a maximum value of 15 µg per amount of MBV consumed daily, and there must be no detectable BMAA levels. Additional economic and manufacturing constraints include wastewater processing to eliminate any potential toxins as well asscale-up to commercial-level production on rotating algal biofilm reactors (RABRs). This project highlights the bioprocess development processfrom initial culture, algal biomass growth on laboratory scale RABRs, scale-up to a greenhouse scale RABR, PCB extraction, and conversion toMBV. This project concludes that MBV production is possible from LLC2 dervied PCB, with both lead and BMAA levels within the given tolerances.